Issue 1

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1

Quantum food and nutrition: Subatomic approaches to nourishment for health and well-being

Author : M Wahlqvist,N Wattanapenpaiboon, M Shuai, H Liu, L Zhong, J Zheng
Keyword : quantum biology, quantum ecobiology, bioenergetics, biorhythms, nutrition
Content : Nutrition science has been represented as biomedical, environmental, societal and economic field, but quantum biology is sidestepped, thereby obscuring cognate problems and solutions. We are generally nourished for health, optimal well-being, longevity and personal security through sustainable livelihoods. Our nourishments include not only food and energy but also light from the sun, the firmament and the earth itself, along with information transmitted in subatomic particles and electromagnetic wave forms. We propose ‘quantum nutrition’ as an approach to reconcile quantum phenomena with nutritional biology. Appreciating quantum nutrition and recognizing its potential applications will provide opportunities for future health and well-being and for planetary habitability.
2

Systematic review on supplementation, fortification, and food-based interventions for preventing iron deficiency anemia in low- and middle-income countries

Author : Systematic review on supplementation, fortification, and food-based interventions for preventing iron deficiency anemia in low- and middle-income countries
Keyword : iron deficiency anemia, iron, vitamin C, supplementation, fortification
Content : Background and Objectives: Prioritizing key preventive and therapeutic interventions is one of the actions to accelerate the reduction of anemia. This study aimed to examine interventions designed to prevent anemia. Methods and Study Design: A systematic search was conducted in PubMed, Web of Science, Scopus, and Cochrane Library. Analysis of publication bias was done using The Joanna-Briggs Institute critical appraisal tool. Data collected from articles included author, year of publication, setting and location of the study, study type, participant of the study, intervention and control given, main outcome, main findings, and risk of bias.
3

Global trends in the revision of nutrient reference values and formulations for infants and toddlers

Author : H Akazawa, C Okada
Keyword : food regulations, Dietary Reference Intakes, nutrition labeling, infants and toddlers, Nutrient Reference Values
Content : Background and Objectives: Nutrient Reference Values (NRVs) play an important role in nutrition labeling and nutrition and health claims based on scientific data. This study, with a global perspective, reviewed recent trends in NRVs for adults and their establishment for infants and toddlers. Methods and Study Design: We searched for laws and regulations on official government websites for nutrition labeling in the United States, Canada, Australia, New Zealand, China, South Korea, Japan, the Codex Committee, and the European Union.
4

Genetically mimicked effects of evinacumab on psoriasis: a drug target Mendelian randomization study

Author : Z Yang, W Xiao, Z Zhuang, S Zhan, M Wang, Y Wu, T Huang, R Li
Keyword : psoriasis, angiopoietin-like 3, evinacumab, lipid metabolism, Mendelian randomization
Content : Background and Objectives: Dyslipidemia has been reported to contribute to the psoriasis pathogenesis. Thus, evinacumab, a novel lipid-lowering drug targeting angiopoietin-like 3, may have therapeutic potential to treat and/or manage psoriasis. Methods and Study Design: Summary statistics were obtained from genome-wide association studies addressing psoriasis (FinnGen Consortium; n=216,752) and serum lipid concentrations (United Kingdom Biobank; n=403,943–440,546). Two-sample Mendelian randomization analyses were conducted to evaluate the associations of serum lipid concentrations and genetically mimicked effects of evinacumab, respectively, with the risks of psoriasis and its subtypes.
5

Dietary, metabolic and gut microbiota influences on primary ovarian failure: a two-sample Mendelian randomization study

Author : X Liu, Z Lin, K Zhu, R He, Z jiang, H Wu, et al
Keyword : primary ovarian failure, dietary factors, metabolic factors, gut microbiota, Mendelian randomization
Content : Background and Objectives: Previous studies have reported there were associations between ovarian function and dietary factors, metabolic factors and gut microbiota. However, it is unclear whether causal associations exist. We aimed to explore the causal relationship of these factors with risk of primary ovarian failure (POF). Methods and Study Design: Two-sample Mendelian randomization (MR) analysis was performed to genetically predict the causal effects of dietary and metabolic factors and gut microbiota on POF. The inverse variance weighted (IVW) method was used as the primary statistical method. A series of sensitivity analyses, including weighted median, MR-Egger, simple mode, weighted mode methods, and leave-one-out analysis, were conducted to assess the robustness of the MR ana...
6

Respiratory quotient as an early predictor of length of stay after cardiac surgery: A prospective observational study

Author : H Ruan, Q Yang,X ZHao, Q Tang, Y Feng
Keyword : respiratory quotient, indirect calorimetry, length of stay, serum lactate, cardiac surgery
Content : Background and Objectives: This study aimed to investigate the respiratory quotient (RQ) levels and its trend in the early postoperative period of patients with heart disease. Additionally, we explored factors influencing RQ and evaluated the predictive capabilities of RQ and lactic acid for various outcomes. Methods and Study Design: In this prospective observational study, participants included were heart disease patients aged 18-80 years who underwent elective open-heart surgery and were subsequently admitted to the cardiothoracic surgery ICU post-operation. Indirect calorimetry (IC) measurements were conducted on patients during the first three days after surgery to assess their RQ levels. Clinical data, including personal information, postoperative characteristics, and duration...
7

Readiness for hospital discharge among patients requiring home nutrition support: a cross-sectional study

Author : C Chen, X Ye, Y Han, J Li, S Liu, R Shen, X Wang
Keyword : readiness for hospital discharge, discharge teaching, home nutrition support, home enteral nutrition, oral nutrition supplements
Content : Background and Objectives: This study aimed to investigate readiness for hospital discharge of patients requiring home nutrition support and explore the factors that influence this readiness. Methods and Study Design: This cross-sectional survey included 220 patients discharged from the general surgery department of a tertiary-care teaching hospital in China with home nutrition support. Readiness for Hospital Discharge Scale and Quality of Discharge Teaching Scale scores were calculated and general, disease- and therapy-related information were collected. Univariate, correlation, and multiple linear regression analyses were performed.
8

Association between serum copper concentration and body composition in children with spinal muscular atrophy: a cross-sectional study

Author : Q Long, Y Feng, Y Yu, F Chen, M Ma, S Mao
Keyword : anthropometric variables, body composition, pediatric patients, serum copper, spinal muscular atrophy
Content : Background and Objectives: The role of serum copper in modulating body composition in patients with spinal muscular atrophy (SMA) remains uncertain. This study aimed to illustrate the correlation between serum copper concentration and body composition in children with SMA. Methods and Study Design: This study was conducted at a pediatric medical center in China from July 2019 to August 2022. The study included anthropometric measurements, serum analysis for copper, magnesium, zinc, and iron, as well as comprehensive body composition assessments. Multivariate analysis was utilized to assess the connection between serum copper concentration and body composition metrics.
9

Associations between diet quality scores and cardiometabolic status in young Japanese women: A cross-sectional study

Author : F Oono, K Murakami, K Uenishi, A Fujiwara, N Shiozaki, S Sasaki, et al
Keyword : diet quality indices, dietary pattern, metabolic syndrome, cardiovascular disease risk, Japan
Content : Background and Objectives: This cross-sectional study aimed to examine associations between diet quality scores and adverse cardiometabolic status in young Japanese women. Methods and Study Design: In total, 1084 female dietetics students aged 18–22 years completed a validated self-administered diet history questionnaire. Diet quality was assessed using the Diet Quality Score for Japanese (DQSJ), Healthy Eating Index-2015 (HEI-2015), Alternate Healthy Eating Index-2010 (AHEI-2010), Alternate Mediterranean Diet score (AMED), Dietary Approaches to Stop Hypertension score (DASH), and Japanese Food Guide Spinning Top score (JFGST). Adverse cardiometabolic status was defined as the highest quartile of the sum of z scores for waist circumference, systolic and diastolic blood pressure, high...
10

Serum magnesium, not calcium, is inversely associated with abnormal HbA1c concentrations in adults with coronary artery disease

Author : H Dong, N Lu, J Wang, P Hu
Keyword : magnesium, calcium, abnormal glycosylated hemoglobin, coronary artery disease, cross–sectional study
Content : Background and Objectives: Mechanism studies have indicated that magnesium (Mg) and calcium (Ca) have important biological functions in glucose regulation, but epidemiological data on their associations with glycosylated hemoglobin (HbA1c) are sparse. We aimed to explore the associations of Mg and Ca with abnormal HbA1c, and examine the mediating effects of inflammation in coronary artery disease (CAD) Chinese adults. Methods and Study Design: A hospital–based cross–sectional study of 11934 patients with CAD was conducted. Serum Mg and Ca concentrations were measured.
11

Association between serum vitamin D and depression among non-alcoholic fatty liver disease

Author : R Jiang, M Lu, Y Hua, Z Hong
Keyword : depression, vitamin D, NAFLD, cross-sectional study
Content : Background and Objectives: While previous population-based studies have suggested a link between serum vitamin D levels and depression in individuals with non-alcoholic fatty liver disease (NAFLD), the exact correlation between serum vitamin D and depression among NAFLD patients remains controversial and disputed. Thus, we conducted this study to evaluate the relationship between serum vitamin D and depression in NAFLD participants diagnosed via transient elastography. Methods and Study Design: This cross-sectional study was extracted from the latest NHANES 2017–2018 dataset. Depression was assessed using the Patient Health Questionnaire-9 (PHQ-9) score of ≥10. NAFLD phenotype was identified by vibration-controlled transient elastography (VCTE) examination based on diagnostic criter...
12

Effects of water-soluble vitamins on glycemic control and insulin resistance in adult type 2 diabetes: an umbrella review of meta-analyses

Author : Y Chai, C Chen, X Yin, X Wang,W Yu, H Pan, et al
Keyword : water-soluble vitamin, type 2 diabetes, glycemic control, insulin resistance, umbrella review
Content : Background and Objectives: Growing evidence has explored the effects of water-soluble vitamins supplementation on glycemic control and insulin resistance in diabetic patients; however, the results of previous meta-analyses are inconsistent. To address this, we conducted an umbrella review to synthesize the evidence on these effects. Methods and Study Design: A systematic literature search in Web of science, PubMed, and Cochrane Database of Systematic Reviews was performed from 2012 to November 2022. he quality of the meta-analyses was assessed using AMSTAR-2 and GRADE.
13

Consumption of fruits, vegetables, and nuts influences the association between serum uric acid and hypertension in Korean adults: A nationwide survey (KNHANES 2016–2021)

Author : Y Shin, E Chang
Keyword : blood pressure, food intake, hypertension, hyperuricemia, uric acid
Content : Background and Objectives: This study investigated the influence of dietary intake on the relationship between serum uric acid (SUA) levels and the risk of hypertension. Methods and Study Design: Data from the 7th and 8th Korean National Health and Nutrition Examination Survey, a nationally representative survey, were analyzed. A total of 19,140 adults aged 19–64 years were included. Dietary intake was assessed using a 24–hour recall method. SUA levels were measured using a Hitachi Automatic Analyzer 7600–210. Hypertension was defined as a systolic blood pressure ≥ 140 mmHg, diastolic blood pressure ≥ 90 mmHg, or the use of antihypertensive medication. Statistical analyses included generalized linear regression, Cochran–Mantel–Haenszel analysis, and multivariate logistic regres...
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