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1

Multivitamin supplements are not superior to nutrition Education in improving fat-soluble vitamin levels: A double-blind randomized controlled trial

Author : S Yusupu, Y Yang, X Geng, Z Lin, T Sun, Z Wang, H Lu, Y Deng
Keyword : fat soluble vitamins, nutrition education, multivitamin supplements, randomized controlled trial, vitamin deficiency
Content : Background and Objectives: Vitamin deficiencies are closely associated with the development of chronic diseases. Therefore, effective and safe intervention strategies are critical to improving vitamin nutritional status. This study aimed to assess the effectiveness and differential impacts of nutrition education and multivitamin supplementation, providing a basis for selecting safer intervention strategies. Methods and Study Design: A 4-week, double-blind, randomized controlled trial was conducted among 155 adults (aged 18–65 years) with confirmed deficiencies in fat-soluble vitamins (A, D, or E).
2

Association of dietary inflammatory index and Chinese healthy eating index with abdominal obesity in kidney transplant recipients

Author : Y Li, Z Zou, H Huang, X Pan, Y Liu, R Tan, et al
Keyword : dietary inflammation index, Chinese healthy eating index, abdominal obesity, kidney transplant recipient, mortality
Content : Background and Objectives: This study investigated associations of the Dietary Inflammatory Index (DII) and Chinese Healthy Diet Index (CHEI) with abdominal obesity in kidney transplant recipients (KTRs), with follow-up analyses further assessing the DII and mortality relationship. Methods and Study Design: We collected anthropometric and biochemical data; dietary consumption was evaluated using 3-day and 24-hour dietary records, with food quality assessed through energy-adjusted DII(E-DII) and CHEI. Binary logistic regression examined the association between E-DII, CHEI, and abdominal obesity in KTRs. The nonlinear connection between E-DII, CHEI, and abdominal obesity was studied using restricted cubic spline (RCS) analysis.
3

Prevalence of hypertension and associated risk factors in tuberculosis patients: a hospital based cross-sectional study

Author : Y Tan, X Gao, Y Li, X Li, Y Liu, X Li, et al
Keyword : tuberculosis, hypertension, prevalence, risk factor, double burden
Content : Background and Objectives: Tuberculosis (TB) is associated with a number of non-communicable diseases including hypertension. The aim of this study is to determine the prevalence of hypertension in TB patients and investigate associated risk factors. Methods and Study Design: A hospital-based cross-sectional study was conducted in Qingdao, China (2011–2019). Data on demographics, medical history, and lifestyle were collected via questionnaire. Blood pressure was measured at admission. Logistic regression identified hypertension risk factors.
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Association between dietary protein intake and preterm birth in pregnant women with gestational diabetes mellitus: the WeBirth cohort study

Author : M Shi, Z Miao, Y Yin, M Ye, X Wang, S Lu, Y Wu, Y Fu, W Hu
Keyword : preterm birth, gestational diabetes mellitus (GDM), protein intake, cohort, FFQ
Content : Background and Objectives: The distribution of dietary macronutrients was essential for blood glucose management in patients with Gestational diabetes mellitus (GDM); However, the relationship between dietary protein intake and the risk of preterm birth remains unclear. Here, we aim to investigate the prospective association between dietary protein intake and preterm birth in patients with GDM. Methods and Study Design: We included 1756 GDM patients and assessed dietary protein patterns by constructing total protein index (TPI), animal protein index (API), and plant protein index (PPI) using data collected from food frequency questionnaires (FFQ).
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Cardiovascular disease burden in China attributable to unbalanced fatty acids intake from 1990 to 2050

Author : X Liu, X Zhang, L Liu, Z Yu, X Qin, Y Ma, X Yang, Y Liu
Keyword : cardiovascular disease, n-3 polyunsaturated fatty acids, trans fatty acids, decomposition analysis, Bayesian Age-Period-Cohort modeling
Content : Background and Objectives: This study aimed to analyze the trends in death and disability-adjusted life years (DALYs) due to cardiovascular disease associated with unbalanced dietary fatty acid intake in China from 1990 to 2021, and to predict the disease burden levels up to 2050. Methods and Study Design: Using Global Burden of Disease 2021 data, we examined death and DALY rates by age, sex, and risk factors. Joinpoint regression assessed temporal trends. Decomposition analysis evaluated contributions of population growth, aging, and epidemiological transitions. Age-period-cohort (APC) modeling estimated cohort and period effects. Bayesian Age-Period-Cohort (BAPC) modeling projected future CVD burden.
6

Systemic inflammatory markers as a supplement to nutrition risk screening of ICU patients

Author : N Tong, Z Huo, N Li, F Chong, S Luo, H Xu
Keyword : critical illness, malnutrition, nutritional risk screening, systemic inflammation, inflammatory markers
Content : Background and Objectives: Critical illness often leads to life-threatening organ dysfunction, requiring intensive care. This catabolic condition significantly affects nutrition, causing muscle loss, weakness, and an increased risk of malnutrition, which complicates recovery. Traditional nutritional assessment tools often face limitations in critically ill patients. Systemic inflammation may improve the accuracy of nutritional risk screening. Methods and Study Design: Data from the MIMIC-IV database were analyzed. The study aimed to assess the prognostic value of inflammatory markers combined with the mNUTRIC score. Survival analyses were conducted using Kaplan-Meier curves and Cox regression models to evaluate the association between these markers and patient mortality at 30-day, 60-...
7

The effect of plant-derived dietary antioxidants on Alzheimer’s disease: Focus on ferroptosis

Author : F Gu, J Zhu, P Zhu, Z Zou
Keyword : Alzheimer’s disease, Ferroptosis, β-amyloid peptide, Tau protein, Plant-derived dietary antioxidants
Content : Background and Objectives: Alzheimer’s disease (AD) is the most prevalent form of dementia in older individuals. Ferroptosis, a programmed cell death characterized by iron-dependent membrane lipid peroxidation is implicated in AD pathology. Increasing evidences have shown that plant-derived dietary antioxidants exhibit their anti-ferroptosis activity. However, the anti-AD mechanism of plant-derived dietary antioxidants remains elusive. Therefore, this review aims to explore the anti-AD effects of plant-derived dietary antioxidants via ferroptosis regulation. Methods and Study Design: This review examines the available published data from all peer-reviewed original research articles on following topics: ferroptosis mechanisms, the role of ferroptosis in AD, the preclinical or clinical...
8

Study on nutritional status and incidence of sarcopenia in elderly patients with chronic heart failure

Author : S Song, H Du, X Lu, B Luo, Z Li
Keyword : elderly patients, chronic heart failure, nutritional status, sarcopenia, body composition analysis
Content : Background and Objectives: Elderly patients with chronic heart failure (CHF) are at high risk of malnutrition and sarcopenia. Therefore, nutritional screening, assessment, diagnosis, and management are particularly crucial for elderly CHF patients. Our study aims to investigate the nutritional status and the incidence characteristics and influencing factors of sarcopenia in elderly CHF patients. Methods and Study Design: A total of 122 elderly CHF patients admitted to The First Hospital of Hebei Medical University from March 2023 to January 2024 were enrolled. Within 24 hours after admission, demographic data, body composition analysis, nutritional status assessments, and laboratory parameter testing were conducted for all participants. Patients were divided into sarcopenia and non-sa...
9

Weight management for adolescents with overweight and obesity: current treatment

Author : L Chen, X Zhu, C Liu
Keyword : weight management, overweight, obesity, adolescent, multicomponent lifestyle intervention
Content : Background and Objectives: The prevalence of overweight or obesity in adolescents is steadily increasing in most countries around the world. Adolescent obesity increases the risk of chronic diseases such as cardiovascular disease, and is associated with negative health consequences, increasing the burden on health services. Methods and Study Design: Literature searching was conducted in PubMed and Google Scholar using the keywords “overweight”, “obesity”, “adolescent”, “weight management”, “dietary management” and “nutritional intervention” combined with Boolean operators “AND” and “OR”.
10

Validity and reliability of the Malaysian Healthy Diet Online Survey (MHDOS) for assessing diet quality in Malaysian adults

Author : F C Woon, J E Wong, Y S Chin, R Selamat, W S Teh, A A Zainuddin, E S Tee, G A Hendrie
Keyword : online survey, diet quality, validity, reliability, dietary assessment
Content : Background and Objectives: Malaysian Healthy Diet Online Survey (MHDOS) is an online survey designed to measure diet quality of Malaysian adults. This study aimed to assess the relative validity and test-retest reliability of the MHDOS. Methods and Study Design: This nationwide cross-sectional study was conducted from May to November 2022 among 218 Malaysian adults. Participants completed the MHDOS, underwent an interview-administered 24-hour diet recall (24DR), and repeated the MHDOS within two weeks. Relative validity was assessed by correlating food group servings from the MHDOS and 24DR using Spearman's correlation coefficients. Construct validity was evaluated by comparing Diet Score tertiles with food group servings, energy, and nutrient intakes from the 24DR.
11

Predictors of carotenoid status in New Zealand children using carotenoid reflection score: a cross-sectional study

Author : J Rapson, E Rush, R Mclean, K Fuavao, C Wall, H Eyles
Keyword : reflection spectroscopy, Veggie Meter, vegetable consumption, potassium, children
Content : Background and Objectives: Optically-assessed skin carotenoid status offers an objective measure of vegetable and fruit intake. Data from the Sodium and Potassium Intake (SNaK+) study was used to explore associations of carotenoid reflection scores with body size, annual household income, vegetable and fruit intake and potassium intake, and the relationship between carotenoid reflection score and 24-hour urinary potassium in children. Methods and Study Design: Seventy-five children (29 girls, 37 boys; 9 not stated) aged 8 to 13 years from five New Zealand primary schools were supported by the parents/caregivers to complete validated questions about their frequency of vegetable and fruit intake.
12

The impact of low-FODMAP diet on symptom relief in patients with irritable bowel syndrome

Author : Y Luo, Z Xu, R Li, Q Zhang, Z Wu
Keyword : low-FODMAP diet, symptom, relief, irritable bowel syndrome, nutrients
Content : Background and Objectives: Irritable bowel syndrome (IBS) stands as a prevalent functional gastrointestinal condition known for causing persistent abdominal pain, changes in bowel patterns, and diminished quality of life. The low fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAP) diet has emerged as a potential approach to managing IBS through dietary adjustments. To explore how the low FODMAP diet affects symptom relief, nutritional well-being, and overall quality of life in IBS patients when compared to those adhering to a standard diet. Methods and Study Design: A retrospective cohort study was conducted, including patients with IBS categorized into a regular diet group and a low FODMAP diet group. Dietary intake, daily nutrient intake, IBS symptom s...
13

Applicability of different resting energy expenditure prediction equations to overweight and obese women of childbearing age with fertility problems

Author : X Wu, H Xue, M Liang, Y Wang, Y Xie, Y Zhai, et al
Keyword : energy expenditure, prediction equations, overweight and obese, women, fertility problems
Content : Background and Objectives: This study compared the accuracy of current energy formulas in predicting resting energy expenditure (REE) in overweight and obese women with fertility problems. Methods and Study Design: This study evaluated REE prediction formulas in 82 overweight/obese women (18-49 years) with fertility problems. REE is accurately measured using indirect calorimetry, which is considered the gold standard for evaluating energy. Anthropometric data, including height, weight, and waist circumference. Body composition analysis was performed using bioelectrical impedance analysis to determine fat-free mass and other related indicators.
14

Effectiveness of a canteen-based dietary intervention for metabolic syndrome in occupational men: A randomized controlled trial

Author : J Ma, Y Zhang, B Liu, Z Du, X Zhang
Keyword : metabolic syndrome, dietary intervention, canteen, randomized controlled trial, occupational men
Content : Background and Objectives: Dietary intervention is an important strategy for the treatment and management of metabolic syndrome (MetS). This study is aimed to investigate the effectiveness of a canteen-based dietary intervention on MetS in occupational men. Methods and Study Design: A randomized controlled study was conducted in May 2022. A total of 321 men with MetS aged 25 to 59 years were recruited from Shengli Oilfield. Participants in one canteen were randomly allocated to dietary intervention group (IG) and those in the other canteen as control group (CG). CG received health education for 6 months. IG received a 6-month healthy lunch and personalized dietary advice added health education. Blood pressure, fasting blood glucose (FBG), lipid profiles, waist circumference (WC) and b...
15

Current practices and future directions of stability testing in parenteral nutrition: A scoping review

Author : N Aina Abu Hassan Shaari, B Kaur Sadu Singh, M Makmor-Bakry, C Menon Premakumar
Keyword : stability tests, parenteral nutrition, parenteral nutrition solutions, all-in-one solutions, lipid emulsions
Content : Background and Objectives: Parenteral nutrition (PN) provides nutrition intravenously, often as two-in-one (TIO) or all-in-one (AIO) solutions. These solutions are complex, containing around 50 chemical components, which can affect the admixture stability. While there is substantial data on stability tests for PN solutions, the methodologies and acceptance criteria are not well-defined in current literature. This scoping review aimed to identify and summarise the current tests and methods used to assess the stability of AIO solutions in hospital settings. Methods and Study Design: Comprehensive searches on stability tests and parenteral nutrition were conducted in Web of Science (WoS), PubMed, and Scopus on 11 January 2024, updated on 4 April 2025.
16

Association between plant dietary fiber intake and hyperuricemia risk in Chinese children aged 6-17 years

Author : L Yu, Z Liu, L Liu, C Liu, C Ma, X Zheng, et al
Keyword : hyperuricemia, dietary fiber, cereals dietary fiber, children, consumption
Content : Background and Objectives: The increasing prevalence of hyperuricemia in children is a global health concern. Plant dietary fiber may influence uric acid levels by improving gut health and lowering blood glucose and lipid levels. This study aims to examine the relationship between plant-based dietary fiber intake and hyperuricemia risk in Chinese children aged 6-17 years. Methods and Study Design: This study analyzed dietary fiber intake data from 11,423 children (aged 6-17 years) from the China Children and Lactating Women Nutrition and Health Surveillance (CCLWNHS) conducted between 2016 and 2019. Plant dietary fiber intake was assessed using a food frequency questionnaire.
17

Do dietary interventions aimed at enhancing fertility improve nutritional status in overweight or obese women?

Author : AF Meisa, V Monal
Keyword : obesity, women, infertility, pregnancy, nutritional status
Content : Background and Objectives: Overweight and obesity represent critical public health challenges, impacting over one-third of the global population. This issue is particularly pressing for women of reproductive age, who are more vulnerable to weight gain. Addressing this connection is vital for promoting overall reproductive health and ensuring the well-being of future generations. This systematic review evaluates the critical relationship between preconception dietary interventions and weight loss, along with their impacts on the nutritional status and fertility of women with obesity. Methods and Study Design: : Our research draws from various literature sources, including CINAHL Plus (EBSCO), Medline, PubMed, the Cochrane Library, Scopus, and the Web of Science Core Collection, coverin...
18

Dietary antioxidant index and cardiometabolic risks in normal-weight individuals: Evidence from the National Health and Nutrition Examination Survey

Author : T Xue, X He, Y Xu, J Fang, M Lin, L Cai, T Zheng, L Li
Keyword : antioxidant, metabolic unhealthy normal weight, nutrition, the National Health and Nutrition Examination Survey, cardiometabolic mortality
Content : Background and Objectives: Caloric restriction is the most popular dietary intervention for preventing metabolic disorders; however, its benefits are limited in normal-weight individuals. This study aimed to examine the association between composite dietary antioxidant index (CDAI) and metabolically unhealthy normal weight (MUNW), as well as the relationship between CDAI and cardiometabolic mortality among normal-weight individuals, in order to provide personalized dietary recommendations. Methods and Study Design: This study consisted of two parts: (1) a cross-sectional analysis exploring the association between CADI and MUNW; and (2) a prospective cohort analysis assessing CDAI in relation to cardiometabolic mortality. Adult participants with normal weight from the National Health a...
19

Exploring causal correlations between oily fish intake and multiple sclerosis: A two-sample Mendelian randomization study

Author : S Chang, K Shi, M Zhang
Keyword : dietary habits, multiple sclerosis, Mendelian randomization, genome-wide association studies, inverse variance weighted
Content : Background and Objectives: According to observational studies, dietary habits may influence the occurrence of multiple sclerosis (MS). There are, however, only a few Mendelian randomization (MR) studies on both. Methods and Study Design: This two-sample MR study’s objective was to examine possible causal associations between the twenty-one dietary practices and MS. For this investigation, we employed MR analysis utilizing generally accessible statistics from genome-wide association studies (GWAS) to examine causal connections between dietary habits and MS susceptibility among persons of European descent.
20

Review of national policies and programs targeting improvement of wasting among under-five years old children in Bangladesh

Author : S Huq,NN Naila,A Alam,G Karmakar, MI Hossain, MM Islam et al.
Keyword : national policies, wasting, children, Bangladesh
Content : Background and Objectives: A balanced diet is critical for health, enhancing immune function and reducing disease risk. Bangladesh's National Nutrition Policy (NNP) focuses on achieving optimal nutrition through secure access to nutritious food across life stages, emphasizing marginalized groups such as mothers, adolescents, and children. Earlier efforts, like the Nutrition Action Plan (1997-2010), addressed maternal and child nutrition but lacked multi-sectoral integration. The revised NNP (2015) employs a collaborative approach, promoting dietary diversity and high-quality food intake. Policies such as the Food Policy Plan of Action (2008-2015) and the Bangladesh National Food and Nutrition Security Policy (2021-2030) further support Sustainable Development Goals (SDGs). Methods and...
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