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1

Myosteatosis mediates the link between specific dietary components and colorectal carcinogenesis: from PPLSS multi-center study

Author : C Li, Y Hsieh, C Li, Y Zhang, L Jiang, S Yu, et al
Keyword : myosteatosis, colorectal cancer, inconspicuous obesity, bean protein, animal-derived nutrients
Content : Background and Objectives: We assumed the specific dietary components may impact colorectal carcinogenesis via ectopic fat accumulation. Methods and Study Design: The multi-center case-control study analyzed CT-derived body composition parameters and dietary intake in 163 colorectal cancer (CRC) patients and 144 non-CRC controls. Ectopic fat distribution was characterized by elevated low-attenuation muscle area (LAMA) and reduced skeletal muscle density (SMD, myosteatosis). We employed logistic regression to assess diet-body composition-CRC associations, mediation analysis to elucidate ectopic fat's role, and random forest modeling to evaluate variable importance in CRC risk prediction.
2

Diet quality of Japanese preschool children assessed by the Healthy Eating Index-2020: Relationships with nutrient and food group intake and weekday–weekend differences

Author : H Akazawa, A Sakai, T Takahashi, T Okabe, R Sasaki, H Ishida, et al
Keyword : child nutrition, diet quality, dietary evaluation, weekdays vs weekends, nutrient profiling system
Content : Background and Objectives: In Japan, there are no official dietary guidelines for young children and nutrients may be insufficient on weekends, compared to weekdays at nursery schools. To ensure adequate nutrition, an appropriate dietary evaluation method is required. This study used the Healthy Eating Index (HEI)-2020, which is based on Dietary Guidelines for Americans, to evaluate the diet quality of Japanese children, examine its validity through associations with nutrient and food group intake, and compare dietary characteristics on weekdays and weekends. Methods and Study Design: The median HEI-2020 score was 50/100, with almost maximum scores for Total Protein Foods, Seafood and Plant Proteins, and Added Sugars, while Whole Grains and Refined Grains scored zero.
3

Healthy eating index, growth status, and household-maternal factors among young children: Evidence from a stunting region in Indonesia

Author : H Herawati, Y Paratmanitya, N Noviani, S Arifiyana, P Sari, A Hadi, et al
Keyword : healthy eating index, diet quality, child nutrition, stunting, household food security
Content : Background and Objectives: Diet quality is a key determinant of child growth, yet little is known about its role in stunting-prevalent regions of Indonesia. This study assessed diet quality of young children using a modified Healthy Eating Index (HEI) and examined its associations with growth status and household–maternal factors. Methods and Study Design: A cross-sectional study was conducted among 215 children aged 12–59 months in Kulon Progo District, Yogyakarta. Dietary intake was assessed using a semi-quantitative food frequency questionnaire and 24-h recall. The HEI was modified to align with Indonesian dietary guidelines and nutrient adequacy standards. Anthropometry, maternal knowledge, education, and household food security were also measured. Children were classified into ...
4

Association between dietary fat intake and fatty acid profiles and hyperuricemia among Chinese adults: Results from the China Health and Nutrition Survey

Author : P Qu, Y Jiao, L Wang, W Li, H Jiang, J Zhang, et al
Keyword : fats, saturated fatty acids, monounsaturated fatty acids, polyunsaturated fatty acids, hyperuricemia
Content : Background and Objectives: Diet is a modifiable factor influencing serum uric acid levels, but evidence on the associations between dietary fat composition and hyperuricemia (HUA) remains limited. This study ex-amined the relationships between the proportion of energy from total fat and specific dietary fatty acids and the risk of HUA among Chinese adults. Methods and Study Design: Data were obtained from adults who participated in at least two follow‑up waves of the China Health and Nutrition Survey (CHNS) in 2009, 2015, and 2018. Associations and dose–response relationships were assessed using multivariate Cox proportional hazards and re-stricted cubic spline (RCS) models.
5

First-week caloric intake and 1-year mortality in critically ill medical patients with mechanical ventilation: A retrospective study

Author : F Wu, W Chao, T Wang, C Wang, Y Wu
Keyword : caloric intake, critical illness, intensive care unit, long-term mortality, nutrition support
Content : Background and Objectives: Higher caloric intake may reduce hospital mortality in critically ill patients at high nutritional risk, but the optimal dose for short-term outcomes remains uncertain and evidence on long-term effects is limited. This study evaluated the association between caloric intake and one-year mortality and identified subgroups that may benefit from higher intake. Methods and Study Design: We conducted a retrospective cohort study in a tertiary medical ICU (2015–2019) including adults receiving mechanical ventilation; ICU stays <48 h were excluded. The exposure was mean caloric intake during ICU days 1–7, defined as total energy from enteral and parenteral routes normalized to body weight. Outcomes included ICU length of stay, ventilator days, and one-year mortali...
6

Dietary inflammatory index and unfavorable dietary patterns associated with ischemic stroke in China

Author : Q Xu, Q Chen, Y Zhuang, L Zhou, L Shen, T Li, et al
Keyword : ischemic stroke, dietary patterns, dietary inflammatory index, risk, case-control study
Content : Background and Objectives: The dietary inflammatory potential, assessed by the Dietary Inflammatory Index (DII), may influence ischemic stroke (IS) risk, but evidence from high-incidence regions in China remains limited. This study aimed to investigate the associations among dietary patterns, the DII, and IS in Eastern China. Methods and Study Design: In a hospital-based case-control study in Zhejiang, China, 223 IS patients and 510 age- and sex-matched controls completed a validated food frequency questionnaire. DII scores were calculated, and dietary patterns were derived using factor analysis. Multivariate logistic regression models were used to calculate odds ratios and 95% confidence intervals (CIs).
7

Malnutrition and associated geriatric syndromes in older outpatients: A comprehensive analysis

Author : B Akpinar, M Karadavut, C Inci, O Avci, M Sasmaz, M Utlu, O Karasahin, P Tasar
Keyword : older adults, malnutrition, risk factors, geriatric syndromes, nutritional status
Content : Background and Objectives: This study aimed to investigate risk factors of malnutrition and the relationship between malnutrition and other geriatric syndromes in patients presenting to a geriatric outpatient clinic in Turkey. Methods and Study Design: The data of patients aged ≥65 years seen in a university geriatric outpatient clinic between January 2024 and January 2025 were retrospectively analyzed. Demographic, clinical, and laboratory data and the results of a comprehensive geriatric assessment were noted. The presence of malnutrition in patients was defined according to the Mini Nutritional Assessment–Long Form.
8

Longitudinal association between exposure to famine in early life and the risk of microvascular complications of type 2 diabetes in adulthood: a retrospective cohort in Tianjin, China

Author : X Cheng, Q Wu, W Zhao, M Li, H Duan, L Huang, et al
Keyword : diabetic microvascular complications, Great Chinese Famine, early life, retrospective cohort, type 2 diabetes
Content : Background and Objectives: Previous studies have linked famine exposure to the incidence of type 2 diabetes (T2D), yet its impact on diabetic microvascular complications (DMC) remains uncertain. This study aims to investigate the longitudinal association between early-life famine exposure and the risk of DMC in adulthood among individuals with T2D. Methods and Study Design: A retrospective cohort study was conducted among inpatients with T2D at Tianjin Medical University Chu Hsien-I Memorial Hospital from June 2014 to June 2022.
9

Evaluating the diet quality of elderly Japanese people using the Healthy Eating Index-2020

Author : H Akazawa, Y Arai, T Koyama,A Sakai, C Okada, et al
Keyword : non-communicable diseases, diet quality, dietary evaluation, dietary reference intakes, nutrient profiling system
Content : Background and Objectives: Globally, efforts are underway to evaluate foods and meals by their nutritional value. In Japan, however, there is no comprehensive system for evaluating overall diet quality. The aim of this study is to use the Healthy Earing Index (HEI)-2020, which is based on the American Dietary Guidelines, to evaluate the diet quality of independent elderly Japanese people to consider appropriate methods for evaluating the Japanese diet. Methods and Study Design: The subjects were 71 individuals aged 60 years or older who participated in a health examination. HEI-2020 was used to evaluate diet quality, with 13 components scored based on intake per energy unit.
10

Effect of whole grain pancakes on postprandial cardiometabolic risk factors in healthy subjects: a randomized crossover trial

Author : Q Ma, T Sun, Z Liu, D Li, X Hu
Keyword : oats, buckwheat, whole grains, pancake, cholesterol
Content : Background and Objectives: Whole grains are rich in nutrients and have multiple health benefits, playing an important role in the diet. This study aims to investigate the acute effects of different whole grain pancakes on cardiometabolic risk factors in healthy subjects. Methods and Study Design: Twenty eligible healthy subjects (aged 19-24 years) were recruited, with baseline measurements including fasting blood glucose, insulin, C-reactive protein (CRP), triglycerides (TG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C).
11

Anaemia and adherence to weekly iron-folic acid supplementation among female senior high school students in stunting-risk areas of Ambon city, Indonesia: Findings from a 2023 cross-sectional survey in Poka and Laha villages

Author : C Titaley, M Malakauseya, R Iwan, E Asmin, R Tahitu, S Aprilla Irene Dea, et al
Keyword : low haemoglobin level, teenage, weekly iron-folic acid supplementation, supplementation compliance
Content : Background and Objectives: Weekly iron-folic acid (IFA) supplementation has been implemented in Indonesia to reduce the prevalence of anaemia in adolescent girls. This study aimed to assess the prevalence of anaemia and adherence to weekly IFA supplementation and their associated factors among adolescent girls in senior high schools in two high-stunting-prone areas of Ambon City, Indonesia. Methods and Study Design: This cross-sectional study was conducted in August–September 2023, involving 645 adolescent girls enrolled at five senior high schools in two high-stunting-prone areas of Ambon City, namely Poka-Rumah Tiga and Laha Village.
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