Non-nutritional anemia: Malaria, thalassemia, G6PD deficiency and tuberculosis in Indonesia
▪ Author : SG Malik, S Oktavianthi, ML Wahlqvist, PBS Asih, A Harahap, AW Satyagraha, D Syafruddin
▪ Keyword : hemoglobin, malaria, thalassemia, G6PD, tuberculosis
▪ Content : Anemia affects people worldwide and results in increased morbidity and mortality, particularly in children and
reproductive-age women. Anemia is caused by an imbalance between red blood cell (RBC) loss and production
(erythropoiesis), which can be caused by not only nutritional factors but also non-nutritional factors, such as inflammation and genetics. Understanding the complex and varied etiology of anemia is crucial for developing effective interventions and monitoring anemia control programs. This review focusses on two interrelated non-nutritional causes of anemia: malaria infection and RBC disorders (thalassemia and G6PD deficiency), as well as
tuberculosis. According to the Haldane hypothesis, thalassemia occurs as a protective trait toward malaria infection, whereas G6PD...