Phentolamine and B vitamins for feeding intolerance in late preterm infants: a randomised trial
▪ Author : YY Lv, N Gao, X He, J Fu, Y Shen, MY Li, Q Zhang and HY Li
▪ Keyword : phentolamine, B vitamins, feeding intolerance, late preterm infants, prematurity
▪ Content : Background and Objectives: Feeding intolerance (FI) is a common problem in late preterm infants (34 weeks ≤ gestational age < 37 weeks). This study aimed to evaluate the efficacy and safety of phentolamine combined with B vitamins in treating FI in late preterm infants and to explore its effects on gastrointestinal symptoms, inflammation and complications. Methods and Study Design: We randomly assigned 118 late preterm infants with FI to a treatment group (n = 56) or a control group (n = 62). The treatment group received intravenous phentolamine and intramuscular B vitamins, whereas the control group received basic treatment only. We measured the time of disappearance of gastrointestinal symptoms, the time of basal attainment, the time of hospitalisation, the incidence of complicatio...