Association between 24 hour urinary α-tocopherol catabolite, 2,5,7,8-tetramethyl-2(2'-carboxyethyl)-6- hydroxychroman (α-CEHC) and α-tocopherol intake in intervention and cross-sectional studies
▪ Author : E Imai, T Tsuji, M Sano, T Fukuwatari, K Shibata
▪ Keyword : α-tocopherol, catabolism, CEHC, urine, biomarker
▪ Content : The objective is to determine the association between the 24 hour urinary α-tocopherol catabolite, 2,5,7,8-
tetramethyl-2(2'-carboxyethyl)-6-hydroxychroman (α-CEHC) and α-tocopherol intake in an intervention and a
cross-sectional studies. In the 4-weeks intervention study, Japanese men (n = 10) consumed the test diet in week
1, and the test diet plus varying amounts of α-tocopherol in the three subsequent weeks: 21 μmol/d α-tocopherol in week 2, 63 μmol/d in week 3, and 125 μmol/d in week 4.