Prevalence, cause and diagnosis of lactose intolerance in children aged 1–5 years: a systematic review of 1995–2015 literature
▪ Author : L Harvey, TL Ludwig, AQ Hou, QS Hock, MLN Tan, S Osatakul, J Bindels, L Muhardi
▪ Keyword : primary lactose intolerance, secondary lactose intolerance, hydrogen breath test, prevalence, children
▪ Content : Background and Objectives: To assess the prevalence, etiology, diagnosis of primary and secondary lactose intolerance (LI), including age of onset, among children 1-5 years of age. Suspected/perceived lactose intolerance can lead to dietary restrictions which may increase risk of future health issues. Methods and Study Design:
MEDLINE, CAB Abstract, and Embase were searched for articles published from January 1995-June 2015 related to lactose intolerance in young children. Authors independently screened titles/abstracts, full text articles, for eligibility against a priori inclusion/exclusion criteria. Two reviewers extracted data and assessed quality of the included studies.