Issue 2

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1

Effect of whole grain pancakes on postprandial cardiometabolic risk factors in healthy subjects: A randomized crossover trial

Author : Qingcui Ma, Tianyu Sun, Zhaoyu Liu, Duo Li, Xiaojie Hu
Keyword : oats, buckwheat, whole grains, pancake, cholesterol
Content : Background and Objectives: Whole grains are rich in nutrients and have multiple health benefits, playing an important role in the diet. This study aims to investigate the acute effects of different whole grain pancakes on cardiometabolic risk factors in healthy subjects. Methods and Study Design: Twenty eligible healthy subjects (aged 19-24 years) were recruited, with baseline measurements including fasting blood glucose, insulin, C-reactive protein (CRP), triglycerides (TG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C). Then, the subjects were randomly allocated into four groups: the steamed bun (SB) group (control group), maize pancake (MP) group, buckwheat pancake (BP) group, and oat pancake (OP) group, with a...
2

First-week caloric intake and 1-year mortality in critically ill medical patients with mechanical ventilation: A retrospective study

Author : Feng-Hsu Wu, Wen-Cheng Chao, Tsai-Jung Wang, Chen-Yu Wang, Yu-Cheng Wu
Keyword : caloric intake, critical illness, intensive care unit, long-term mortality, nutrition support
Content : Background and Objectives: Higher caloric intake may reduce hospital mortality in critically ill patients at high nutritional risk, but the optimal dose for short-term outcomes remains uncertain and evidence on long-term effects is limited. This study evaluated the association between caloric intake and one-year mortality and identified subgroups that may benefit from higher intake. Methods and Study Design: We conducted a retrospective cohort study in a tertiary medical ICU (2015–2019) including adults receiving mechanical ventilation; ICU stays <48 h were excluded. The exposure was mean caloric intake during ICU days 1–7, defined as total energy from enteral and parenteral routes normalized to body weight. Outcomes included ICU length of stay, ventilator days, and one-year mortali...
3

Association between the frequency of combined staple, main, and side dishes and nutritional adequacy among young Japanese women: A cross-sectional study

Author : Akinori Yaegashi, Ai Ota, Aki Shirahata, Hiyori Takada, Miki Nakamura, Hizuru Katou, Miyuki Kozuka
Keyword : staple food, Japanese, nutritional adequacy, young woman, nutritional epidemiology
Content : Background and Objectives: Traditional Japanese diet comprises staple food, main dish, and side dish (SMS). Studies reporting the association between the frequency of SMS meals consumption and nutritional adequacy remain limited. We aimed to examine the association between the frequency of SMS meals consumption and nutritional adequacy in young Japanese women. Methods and Study Design: In this cross-sectional study, data from 329 female nutrition students aged 18–25 years were analysed. The frequency of SMS meals consumption more than twice a day was assessed using a self-administered questionnaire, and dietary intake was evaluated using a validated food frequency questionnaire. We examined the association between SMS meals consumption and likelihood of not meeting the Dietary Goal (...
4

Association between dietary patterns and depressive symptoms in Chinese adults

Author : Shaopeng Guo, Xiaohui Sun, Kejia Huang, Chi Pan, Xiao Liu, Weijing Wang, Feng Ning, Jie Xu, Ao Li, Dongfeng Zhang, Hairong Nan
Keyword : dietary pattern, depressive symptoms, adult, cross-sectional study, restricted cubic spline analysis
Content : Background and Objectives: This cross-sectional study explored the association between dietary patterns and depressive symptoms in middle-aged and older individuals in China. Methods and Study Design: A total of 2,956 individuals aged 45-74 years were included in the current data analysis, based on a community-based cross-sectional study from Qingdao, China. Data for this study were derived from field surveys conducted from August 2009 to November 2010. Their mean age was 57.2 ± 8.46 years, and 62.4% were women. Dietary intake was assessed using a validated semi-quantitative food frequency questionnaire (SQFFQ). Dietary patterns were derived using principal component analysis. Depressive symptoms were assessed using the validated Zung Self-Rating Depression Scale. Logistic regression ...
5

Anaemia and adherence to weekly iron-folic acid supplementation among female senior high school students in stunting-risk areas of Ambon city, Indonesia

Author : Christiana Rialine Titaley, Maxwell Landri Vers Malakauseya, Ressita Fannia Iwan, Elpira Asmin, Ritha Tahitu, Sixtintia Aprilla Irene Dea, Yudhie Djuhastidar Tando, Liyani Sartika Sara, Ina Kusrini, Dwi Hapsari Tjandrarini
Keyword : low haemoglobin level, teenage, weekly iron-folic acid supplementation, supplementation compliance
Content : Background and Objectives: Weekly iron-folic acid (IFA) supplementation has been implemented in Indonesia to reduce the prevalence of anaemia in adolescent girls. This study aimed to assess the prevalence of anaemia and adherence to weekly IFA supplementation and their associated factors among adolescent girls in senior high schools in two high-stunting-prone areas of Ambon City, Indonesia. Methods and Study Design: This cross-sectional study was conducted in August–September 2023, involving 645 adolescent girls enrolled at five senior high schools in two high-stunting-prone areas of Ambon City, namely Poka-Rumah Tiga and Laha Village. The dependent variables were anaemia (i.e., haemoglobin level <12 g/dL) and adherence to weekly IFA supplementation (i.e., consumption of one IFA tabl...
6

Longitudinal association between early-life famine exposure and risk of microvascular complications of type 2 diabetes in adulthood: A retrospective cohort in Tianjin, China

Author : Xiaocui Cheng, Qi Wu, Wei Zhao, Mingzhen Li, Huilian Duan, Li Huang, Tongtong Li, Zehao Wang, Cheng Cheng, Xukun Chen, Liyang Zhang, Yongjie Chen, Guowei Huang
Keyword : diabetic microvascular complications, Great Chinese Famine, early life, retrospective cohort, type 2 diabetes
Content : Background and Objectives: Previous studies have linked famine exposure to the incidence of type 2 diabetes (T2D), yet its impact on diabetic microvascular complications (DMC) remains uncertain. This study aims to investigate the longitudinal association between early-life famine exposure and the risk of DMC in adulthood among individuals with T2D. Methods and Study Design: A retrospective cohort study was conducted among inpatients with T2D at Tianjin Medical University Chu Hsien-I Memorial Hospital from June 2014 to June 2022. The 2409 participants were divided into five famine exposure groups based on birth years: no exposure group (1962-1965), fetal period exposure group (1959-1961), early-childhood exposure group (1956-1958), mid-childhood exposure group (1953-1955), and late-chi...
7

Association between dietary fat intake and fatty acid profiles and hyperuricemia among Chinese adults: Results from the China Health and Nutrition Survey

Author : Pengfeng Qu, Yingying Jiao, Liusen Wang, Weiyi Li , Hongru Jiang, Jiguo Zhang, Huijun Wang, Bing Zhang, Junhua Han, Aidong Liu, Zhihong Wang
Keyword : fats, saturated fatty acids, monounsaturated fatty acids, polyunsaturated fatty acids, hyperuricemia
Content : Background and Objectives: Diet is a modifiable factor influencing serum uric acid levels, but evidence on the associations between dietary fat composition and hyperuricemia (HUA) remains limited. This study examined the relationships between the proportion of energy from total fat and specific dietary fatty acids and the risk of HUA among Chinese adults. Methods and Study Design: Data were obtained from adults who participated in at least two follow‑up waves of the China Health and Nutrition Survey (CHNS) in 2009, 2015, and 2018. Associations and dose–response relationships were assessed using multivariate Cox proportional hazards and restricted cubic spline (RCS) models.
8

Myosteatosis mediates the link between specific dietary components and colorectal carcinogenesis: from PPLSS multi-center study

Author : Chun-wei Li, Yifang Hsieh, Chao Li, Yu Zhang, Ling-juan Jiang, Song-lin Yu, Long-Chun Dong, Zhi-quan Tan, Judong Zhang, Jing Xu, Kang Yu
Keyword : myosteatosis, colorectal cancer, inconspicuous obesity, bean protein, animal-derived nutrients
Content : Background and Objectives: We assumed the specific dietary components may impact colorectal carcinogenesis via ectopic fat accumulation. Methods and Study Design: The multi-center case-control study analyzed CT-derived body composition parameters and dietary intake in 163 colorectal cancer (CRC) patients and 144 non-CRC controls. Ectopic fat distribution was characterized by elevated low-attenuation muscle area (LAMA) and reduced skeletal muscle density (SMD, myosteatosis). We employed logistic regression to assess diet-body composition-CRC associations, mediation analysis to elucidate ectopic fat's role, and random forest modelling to evaluate variable importance in CRC risk prediction.
9

Dietary inflammatory index and unfavorable dietary patterns associated with ischemic stroke in China

Author : Qunli Xu, Qianyi Chen, Yiyu Zhuang, Lanlan Zhou, Lanjun Shen, Tingting Li, Zhefang Hu, Ronghua Zhang, Danting Su, Lijun Feng
Keyword : ischemic stroke, dietary patterns, dietary inflammatory index, risk, case-control study
Content : Background and Objectives: The dietary inflammatory potential, assessed by the Dietary Inflammatory Index (DII), may influence ischemic stroke (IS) risk, but evidence from high-incidence regions in China remains limited. This study aimed to investigate the associations among dietary patterns, the DII, and IS in Eastern China. Methods and Study Design: In a hospital-based case-control study in Zhejiang, China, 223 IS patients and 510 age- and sex-matched controls completed a validated food frequency questionnaire. DII scores were calculated, and dietary patterns were derived using factor analysis. Multivariate logistic regression models were used to calculate odds ratios and 95% confidence intervals (CIs).
10

Diet quality of Japanese preschool children assessed by the Healthy Eating Index-2020: Nutrient and food group intake, as well as weekday–weekend differences

Author : Hazuki Akazawa, Atsuki Sakai, Takako Takahashi, Tetsuko Okabe, Ruriko Sasaki, Hiromi Ishida, Hiromitsu Ogata, Mitsuhiko Hara, Yukiko Yoshioka, Miho Nozue, Tatsuaki Sakamoto, Sanae Ito, Nobuko Murayama, Katsushi Yoshita
Keyword : child nutrition, diet quality, dietary evaluation, weekdays vs weekends, nutrient profiling system
Content : Background and Objectives: In Japan, there are no official dietary guidelines for young children and nutrients may be insufficient on weekends, compared to weekdays at nursery schools. To ensure adequate nutrition, an appropriate dietary evaluation method is required. This study used the Healthy Eating Index (HEI)-2020, which is based on the Dietary Guidelines for Americans, to evaluate the diet quality of Japanese children, examine its validity through associations with nutrient and food group intake, and compare dietary characteristics on weekdays and weekends. Methods and Study Design: The participants were 669 children aged 3 to 5 years attending nursery schools across Japan. Relationships of HEI-2020 scores with nutrient and food group intake, and comparisons between weekdays and...
11

Healthy eating index, growth status, and household-maternal factors among young children: Evidence from a stunting region in Indonesia

Author : Herni Dwi Herawati, Yhona Paratmanitya, Nor Eka Noviani, Siska Arifiyana, Pramitha Sari, Arinto Hadi, Lisana Shidiq Aliya, Tsabita Azza Faiza, Kholifah Rista Utami, Titis Sela Herfadea, Tri Artika Ardhiani Irawan
Keyword : healthy eating index, diet quality, child nutrition, stunting, household food security
Content : Background and Objectives: Diet quality is a key determinant of child growth, yet little is known about its role in stunting-prevalent regions of Indonesia. This study assessed diet quality of young children using a modified Healthy Eating Index (HEI) and examined its associations with growth status and household–maternal factors. Methods and Study Design: A cross-sectional study was conducted among 215 children aged 12–59 months in Kulon Progo District, Yogyakarta. Dietary intake was assessed using a semi-quantitative food frequency questionnaire and 24-h recall. The HEI was modified to align with Indonesian dietary guidelines and nutrient adequacy standards. Anthropometry, maternal knowledge, education, and household food security were also measured. Children were classified into ...
12

The association between polyunsaturated fatty acids in breast milk and infant eczema and its relationship with infant gut microbiota

Author : Zeqi Li, Kelei Li, Xiao Wu, Lu Lin, Yongye Sun
Keyword : infant eczema, breast milk, fatty acids, polyunsaturated fatty acids, gut microbiota
Content : Background and Objectives: Current evidence on the relationship between breast milk fatty acids and infant eczema is limited. The present study aimed to investigate the association between polyunsaturated fatty acids (PUFAs) in breast milk and the incidence of infant eczema and its relationship with infant gut microbiota. Methods and Study Design: Twenty-five infants diagnosed with eczema and fifty healthy infants born during the same period were recruited at 1 month postpartum. A follow-up was conducted on healthy infants at 6 months postpartum to determine if any new-onset eczema occurred. Breast milk and infant feces were collected at each interview.
13

Evaluating the diet quality of elderly Japanese using the Healthy Eating Index-2020

Author : Hazuki Akazawa, Yusuke Arai, Tatsuya Koyama, Atsuki Sakai, Chika Okada, Yuko Tousen, Jun Takebayashi, Hidemi Takimoto, Katsushi Yoshita
Keyword : non-communicable diseases, diet quality, dietary evaluation, dietary reference intakes, nutrient profiling system
Content : Background and Objectives: Globally, efforts are underway to evaluate foods and meals by their nutritional value. In Japan, however, there is no comprehensive system for evaluating overall diet quality. The aim of this study is to use the Healthy Eating Index (HEI)-2020, which is based on the American Dietary Guidelines, to evaluate the diet quality of independent elderly Japanese people to consider appropriate methods for evaluating the Japanese diet. Methods and Study Design: The subjects were 71 individuals aged 60 years or older who participated in a health examination. HEI-2020 was used to evaluate diet quality, with 13 components scored based on intake per energy unit. Associations of HEI-2020 scores with nutrient intake, food group intake, and dietary reference intakes (DRIs) ...
14

Malnutrition and associated geriatric syndromes in older outpatients: A comprehensive analysis

Author : Busra Akpinar, Mursel Karadavut, Cemil İnci, Ozlem Avci, Merve Erat Sasmaz, Mustafa Utlu, Omer Karasahin, Pinar Tosun Tasar
Keyword : older adults, malnutrition, risk factors, geriatric syndromes, nutritional status
Content : Background and Objectives: This study aimed to investigate risk factors of malnutrition and the relationship between malnutrition and other geriatric syndromes in patients presenting to a geriatric outpatient clinic in Turkey. Methods and Study Design: The data of patients aged ≥65 years seen in a university geriatric outpatient clinic between January 2024 and January 2025 were retrospectively analyzed. Demographic, clinical, and laboratory data and the results of a comprehensive geriatric assessment were noted. The presence of malnutrition in patients was defined according to the Mini Nutritional Assessment–Long Form.
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