Volume 24 Supplement 1

▪ Keyword : Lactase persisters (LP), Lactase non-persisters (LNP), rs49882359 allele, gut microbiome, dairy food tolerance test (DFTT)

▪ Content : The concept of lactose intolerance has become embedded in Western medicine and developing economy medicine. It is based on evidence that intestinal lactase activity persists into later childhood and throughout life in only a minority of the world’s population, notably northern European–derived populations.

▪ Keyword : hydrogen breath test, lactose intolerance, lactase

▪ Content : Lactose is the main carbohydrate in infant feeding, but its impact decreases as the child gets older and consumes less milk and dairy products. Congenital lactose intolerance is a very rare condition. However, lactase activity may be low and need to mature during the first weeks of life in many infants.

▪ Keyword : dairy, health, stroke, lactase persistence, Taiwan

▪ Content : The health relevance of dairy products has mostly been judged by their abundant nutrients (protein, calcium and riboflavin) and recommendations for these derived in lactase-persistent Caucasian populations. Extrapolation to Asians who are generally lactase non-persisters may not be biologically, culturally or environmentally sound.

▪ Keyword : lactase persisters, lactose nutrition, lactose intolerance, cathelicidin antimicrobial peptide (CAMP), innate immunity

▪ Content : Lactose handling by the human gut by most people, beyond being breast-fed, has been considered a disorder rather than physiological. A non-human mammalian milk source is novel for the majority. During the first 6 months of life, when neonates and infants are best breast-fed, lactose along with other macronutrients, provides energy, but may have other functions as well.

▪ Keyword : Indonesian dairy foods, minyak samin, dadih, dali, dangke, litsusu, cologanti

▪ Content : Indonesia is the largest archipelago blessed with one of the richest mega-biodiversities and also home to one of the most diverse cuisines and traditional fermented foods. There are 3 types of traditional dairy foods, namely the butter-like product minyak samin; yogurt-like product dadih; and cheese-like products dali or bagot in horbo, dangke, litsusu, and cologanti, which reflect the culture of dairy product consumption in Indonesia.

▪ Keyword : lactose intolerance, lactose malabsorption, children, lactase deficiency, Indonesia

▪ Content : “Lactose intolerance (LI)” is considered a common problem in Asians, and in many parts of the world. Its prevalence and age of manifestation varies between by Asian country, for possible genetic or cultural reasons. Studies in Indonesian children 3-15 years old (y) are available within the past two decades, using a pure lactose tolerance test. The prevalences of lactose malabsorption (LM) in pre-elementary (3-5 y), elementary (6-11 y), and junior high (12-14 y) school-children were 21.3%, 57.8%, and 73%, respectively.